Química de Biomoléculas

Espécies “Reativas” de Oxigênio - Processos Redox

Oxigênio Molecular Singlete

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Principais resultados obtidos Período (2007-2012)

1. Agnez-Lima, Lucymara F., Melo, Julliane T.A., Silva, Acarízia E., Oliveira, Ana Helena S., Timoteo, Ana Rafaela S., Lima-Bessa, Keronninn M., Martinez, Glaucia R., Medeiros, Marisa H.G., Di Mascio, Paolo, Galhardo, Rodrigo S., Menck, Carlos F.M.
DNA damage by singlet oxygen and cellular protective mechanisms. Mutation Research. Reviews in Mutation Research (Print). , v.1, p.1 - , 2012.

2. Suzukawa, Andréia Akemi, Vieira, Alessandra, Winnischofer, Sheila Maria Brochado, Scalfo, Alexsandra Cristina, Di Mascio, Paolo, Ferreira, Ana Maria da Costa, Ravanat, Jean-Luc, Martins, Daniela de Luna, Rocha, Maria Eliane Merlin, Martinez, Glaucia Regina
Novel properties of melanins include promotion of DNA strand breaks, impairment of repair, and reduced ability to damage DNA after quenching of singlet oxygen. Free Radical Biology & Medicine. , v.52, p.1945 - 1953, 2012.

3. Garcia, Camila Carria?o M., Angeli, Jose? Pedro F., Freitas, Flore?ncio P., Gomes, Osmar F., de Oliveira, Tiago F., Loureiro, Ana Paula M., DI MASCIO, P., Medeiros, Marisa H. G., MEDEIROS, M. H. G.
[ C ]- Acetaldehyde Promotes Unequivocal Formation of 1, -Propano-2?-deoxyguanosine in Human Cells. Journal of the American Chemical Society (Print). , v.133, p.9140 - 9143, 2011.

4. UEMI, Miriam, Ronsein, Graziella E., Prado, Fernanda M., Motta, Flávia D., Miyamoto, Sayuri, Medeiros, Marisa H. G., Di Mascio, Paolo
Cholesterol Hydroperoxides Generate Singlet Molecular Oxygen [O. Chemical Research in Toxicology. , v.24, p.887 - 895, 2011.

5. Ronsein, Graziella E., de Oliveira, Mauricio Cesar Bof, Medeiros, Marisa H. G., Miyamoto, Sayuri, Di Mascio, Paolo
DNA strand breaks and base modifications induced by cholesterol hydroperoxides. Free Radical Research. , v.45, p.266 - 275, 2011.

6. Massari, Júlio, Tokikawa, Rita, Medinas, Danilo B., Angeli, José P. F., Di Mascio, Paolo, Assunção, Nilson A., Bechara, Etelvino J. H.
Generation of Singlet Oxygen by the Glyoxalâ¿"Peroxynitrite System. Journal of the American Chemical Society (Print). , v.133, p.20761 - 20768, 2011.

7. Angeli, José Pedro F., Garcia, Camila Carrião M., Sena, Fernanda, Freitas, Florencio P., Miyamoto, Sayuri, Medeiros, Marisa Helena G., Di Mascio, Paolo
Lipid hydroperoxide-induced and hemoglobin-enhanced oxidative damage to colon cancer cells. Free Radical Biology & Medicine. , v.51, p.503 - 515, 2011.

8. Almeida, Eduardo Alves, Mascio, Paolo, Harumi, Tatsuo, Warren Spence, D., Moscovitch, Adam, Hardeland, Rüdiger, Cardinali, Daniel P., Brown, Gregory M., Pandi-Perumal, S. R., Di Mascio, Paolo
Measurement of melatonin in body fluids: Standards, protocols and procedures. Child's Nervous System (Print). , v.27, p.879 - 891, 2011.

9. Ronsein, G. E., de Oliveira, Mauricio Cesar Bof, de Medeiros, Marisa Helena Gennari, Di Mascio, Paolo
Mechanism of dioxindolylalanine formation by singlet molecular oxygen-mediated oxidation of tryptophan residues. Photochemical & Photobiological Sciences (Print). , v.10, p.1727 - , 2011.

10. Zanette, Juliano, de Almeida, Eduardo Alves, da Silva, Angela Zaccaron, Guzenski, João, Ferreira, Jaime Fernando, Di Mascio, Paolo, Marques, Maria Risoleta Freire, BAINY, Afonso Celso Dias
Salinity influences glutathione S-transferase activity and lipid peroxidation responses in the Crassostrea gigas oyster exposed to diesel oil. Science of the Total Environment. , v.409, p.1976 - 1983, 2011.

11. Oliveira, Marilene S., Severino, Divinomar, Prado, Fernanda M., Angeli, José Pedro F., Motta, Flávia D., Baptista, Maurício S., Medeiros, Marisa H. G., Di Mascio, Paolo
Singlet molecular oxygen trapping by the fluorescent probe diethyl-3,3⿲-(9,10-anthracenediyl)bisacrylate synthesized by the Heck reaction. Photochemical & Photobiological Sciences (Print). , v.10, p.1546 - 1555, 2011.

12. Matiolli, C. C., Tomaz, J. P., Duarte, G. T., PRADO, F. M., Del Bem, L. E. V., Silveira, A. B., Gauer, L., Correa, L. G. G., Drumond, R. D., Viana, A. J. C., Mascio, P. D., Meyer, C., Vincentz, M. G. A., DI MASCIO, P.
The Arabidopsis bZIP gene AtbZIP63 is a sensitive integrator of transient ABA and glucose signals. Plant Physiology (Bethesda). , v.157, p.692 - 705, 2011.

13. Ronsein, Graziella E., Prado, Fernanda M., Mansano, Fernando V., Oliveira, Mauricio C. B., Medeiros, Marisa H. G., MIYAMOTO, Sayuri, Di Mascio, Paolo
Detection and Characterization of Cholesterol-Oxidized Products Using HPLC Coupled to Dopant Assisted Atmospheric Pressure Photoionization Tandem Mass Spectrometry. Analytical Chemistry (Washington). , v.82, p.7293 - 7301, 2010.

14. Carneiro, Carlos D., Amorim, Juliana C., Cadena, Silvia M.S.C., Noleto, Guilhermina R., Di Mascio, Paolo, Rocha, Maria E.M., Martinez, Glaucia R.
Effect of flavonoids on 2?-deoxyguanosine and DNA oxidation caused by singlet molecular oxygen. Food and Chemical Toxicology. , v.48, p.2380 - 2387, 2010.

15. Mansano, Fernando V., Kazaoka, Rafaella M. A., Ronsein, Graziella E., Prado, Fernanda M., Genaro-Mattos, Thiago C., UEMI, Miriam, Di Mascio, Paolo, MIYAMOTO, Sayuri
Highly Sensitive Fluorescent Method for the Detection of Cholesterol Aldehydes Formed by Ozone and Singlet Molecular Oxygen. Analytical Chemistry (Washington). , v.82, p.6775 - 6781, 2010.

16. Barbosa, Livea F., Cerqueira, Fernanda M., Macedo, Antero F.A., Garcia, Camila C.M., Angeli, José Pedro F., Schumacher, Robert I., Sogayar, Mari Cleide, AUGUSTO, Ohara, Carrì, Maria Teresa, Di Mascio, Paolo
Increased SOD1 association with chromatin, DNA damage, p53 activation, and apoptosis in a cellular model of SOD1-linked ALS. Biochimica et Biophysica Acta. Molecular Basis of Disease. , v.1802, p.462 - 471, 2010.

17. Berra, Carolina Maria, Menck, Carlos Frederico Martins, Martinez, Glaucia Regina, Oliveira, Carla Santos de, Baptista, Maurício da Silva, Di Mascio, Paolo
Plasmid DNA damage induced by singlet molecular oxygen released from the naphthalene endoperoxide DHPNO2 and photoactivated methylene blue. Química Nova (Impresso). , v.33, p.279 - 283, 2010.

18. do Nascimento, Gustavo M., de Oliveira, Rafael C., Pradie, Noriberto A., Lins, Paulo R. Gessolo, Worfel, Paulo R., Martinez, Glaucia R., Di Mascio, Paolo, Dresselhaus, Mildred S., Corio, Paola
Single-wall carbon nanotubes modified with organic dyes: Synthesis, characterization and potential cytotoxic effects. Journal of Photochemistry and Photobiology. A, Chemistry. , v.211, p.99 - 107, 2010.

19. Garcia, Camila C. M., Freitas, Flore?ncio P., Di Mascio, Paolo, Medeiros, Marisa H. G.
Ultrasensitive Simultaneous Quantification of 1, -Etheno-2?-deoxyguanosine and 1, -Propano-2?-deoxyguanosine in DNA by an Online Liquid Chromatography?Electrospray Tandem Mass Spectrometry Assay. Chemical Research in Toxicology. , v.23, p.1245 - 1255, 2010.

20. Yamaguchi, L. F., Kato, M.J., Di Mascio, P.
Biflavonoids from Araucaria angustifolia protect against DNA UV-induced damage. Phytochemistry. , v.70, p.615 - 620, 2009.

21. Ronsein, Graziella Eliza, de Oliveira, Mauricio Cesar Bof, Medeiros, M. H. G., Di Mascio, P., Medeiros, M. H. G.
Characterization of O2 (1?g)-Derived Oxidation Products of Tryptophan: A Combination of Tandem Mass Spectrometry Analyses and Isotopic Labeling Studies. Journal of the American Society for Mass Spectrometry. , v.20, p.188 - 197, 2009.

22. Miyamoto, S., Ronsein, G. E., Correa, T. C., Martinez, G. R., Medeiros, M. H. G., Di Mascio, P.
Direct evidence of singlet molecular oxygen generation from peroxynitrate, a decomposition product of peroxynitrite. Dalton Transactions. , v.1, p.1 - , 2009.

23. Barbosa, L F, Garcia, C C M, Di Mascio, P., Medeiros, M H G.
DNA oxidation, strand-breaks and etheno-adducts formation promoted by Cu, Zn-superoxide dismutase-H2O2 in the presence and absence of bicarbonate. Dalton Transactions. , v.8, p.1450 - 1459, 2009.

24. Uemi, M., Ronsein, G. E., Miyamoto, S., Medeiros, M. H. G., Di Mascio, P.
Generation of Cholesterol Carboxyaldehyde by the Reaction of Singlet Molecular Oxygen [O2 (1?g)] as Well as Ozone with Cholesterol. Chemical Research in Toxicology. , v.22, p.875 - 884, 2009.

25. Pueyo, M. T., Bloch Jr. C., Carmona-Ribeiro, A. M., Di Mascio, P.
Lipopeptides Produced By A Soil Bacillus Megaterium Strain. Microbial Ecology. , V.57, P.367 - 378, 2009.

26. Vaz, S.M., PRADO, F. M., DI MASCIO, P., AUGUSTO, O.
Oxidation And Nitration Of Ribonuclease And Lysozyme By Peroxynitrite And Myeloperoxidase. Archives Of Biochemistry And Biophysics (Print). , V.484, P.127 - 133, 2009.

27. KAWAI, C, Pessoto, F.S., RODRIGUES, T, Mugnol, K.C.U., Tórtora, V, Castro, L, Milícchio, V.A., Tersariol, Ils, Di Mascio, P., Radi, R, Carmona-Ribeiro, A. M., Nantes, I. L.
pH-Sensitive Binding of Cytochrome to the Inner Mitochondrial Membrane. Implications for the Participation of the Protein in Cell Respiration and Apoptosis. Biochemistry (Easton). , v.48, p.8335 - 8342, 2009.

28. Cadet, Jean, Douki, Thierry, Ravanat, Jean-Luc, Di Mascio, Paolo
Sensitized formation of oxidatively generated damage to cellular DNA by UVA radiation. Photochemical & Photobiological Sciences (Print). , v.8, p.903 - , 2009.

29. Prado, F. M., Oliveira, M. C. B., Miyamoto, S., Martinez, G. R., Medeiros, M. H. G., Ronsein, G. E., Di Mascio, P.
Thymine hydroperoxide as a potential source of singlet molecular oxygen in DNA. Free Radical Biology & Medicine. , v.1, p.1 - , 2009.

30. Ronsein, G, Bofdeoliveira, M, Gennaridemedeiros, M, Di Mascio, P.
Characterization of O2 (1?g)-Derived Oxidation Products of Tryptophan: A Combination of Tandem Mass Spectrometry Analyses and Isotopic Labeling Studies. Journal of the American Society for Mass Spectrometry. , p.x - , 2008.

31. Keppler, A, Prado, F, Cerchiaro, G, Di Mascio, P., Comasseto, J.
Mechanistic study of the addition reaction of TeCl4 to alkynes: Participation of TeCl3 centered-radical. Journal of Organometallic Chemistry. , p.x - , 2008.

32. SIGOLO, Carlos Alexandre Oliveira, DI MASCIO, P., Kowaltowski AJ, GARCIA, C. C. M., Medeiros, M. H. G.
Trans, trans-2,4-Decadienal Induces Mitochondrial Dysfunction and Oxidative Stress. Journal of Bioenergetics and Biomembranes. , v.40, p.103 - 109, 2008.

33. SIGOLO, C. A.O., DI MASCIO, P., KOWALTOWSKI, A. J., GARCIA, C C M, MEDEIROS, M. H. G.
trans, trans-2,4-decadienal induces mitochondrial dysfunction and oxidative stress. Journal of Bioenergetics and Biomembranes. , v.40, p.103 - 109, 2008.

34. Ronsein, G. E., Oliveira, M. C. B., Miyamoto, S., Medeiros, M. H. G., Di Mascio, P.
Tryptophan Oxidation by Singlet Molecular Oxygen [O2 (1?g)]: Mechanistic Studies Using 18O-Labeled Hydroperoxides, Mass Spectrometry, and Light Emission Measurements. Chemical Research in Toxicology. , v.21, p.1271 - 1283, 2008.

35. Miyamoto, S., Ronsein, G. E., Prado, F. M., Uemi, M., Correa, T. C., Toma, I. N., Oliveira, M. C. B., Motta, F. D., Medeiros, M. H. G., Di Mascio, P.
Biological hydroperoxides and singlet molecular oxygen generation. IUBMB Life (London). , v.59, p.322 - 331, 2007.

36. Sigolo, C. A.O., Di Mascio, P., Medeiros, M. H. G.
Covalent modification of cytochrome c exposed to trans,trans-2,4-decadienal. Chemical Research in Toxicology. , v.20, p.1099 - 1110, 2007.

37. Carreira, R. S., Miyamoto, S., Di Mascio, P., Goncalves, L. M., Monteiro, P., Providencia, L. A., Kowaltowski, A. J.
Ischemic preconditioning enhances fatty acid-dependent mitochondrial uncoupling. Journal of Bioenergetics and Biomembranes. , v.39, p.313 - 320, 2007.

38. Tan, D-X., Manchester, L. C., Di Mascio, P., Martinez, G. R., Prado, F. M., Reiter, R. J.
Novel rhythms of N1-acetyl-N2-formyl-5-methoxykynuramine and its precursor melatonin in water hyacinth: importance for phytoremediation. The FASEB Journal. , v.21, p.1724 - 1729, 2007.

39. Alvesdealmeida, E, Celsodiasbainy, A, Paulademeloloureiro, A, Reginamartinez, G, Miyamoto, S, Onuki, J, Fujitabarbosa, L, Carriaomachadogarcia, C, Mansoprado, F, Elizaronsein, G, Di Mascio, P.
Oxidative stress in Perna perna and other bivalves as indicators of environmental stress in the Brazilian marine environment: Antioxidants, lipid peroxidation and DNA damage?. Comparative Biochemistry and Physiology. A, Molecular & Integrative Physiology. , v.146, p.588 - 600, 2007.

40. Araujo, J. C., Prieto, T., Prado, F. M., Trindade, F. J., Nunes, G. L., Santos, J. G., Di Mascio, P., Castro, F. L., Fernandes, G. J., Fernandes, V. J., Araujo, A. S., Politi, M. J., Brochsztain, S., Nascimento, O. R., Nantes, I. L.
Peroxidase catalytic cycle of MCM-41-entrapped microperoxidase-11 as a mechanism for phenol oxidation. Journal of Nanoscience and Nanotechnology. , v.7, p.1 - 10, 2007.

41. Oliveira, M.S., Lima, M., Severino, D., Baptista, M S, Di Mascio, P., Tabak, M.
Quenching of singlet molecular oxygen, 02(1Dg), by dipyridamole and derivatives. Photochemistry and Photobiology. , v.83, p.1379 - 1385, 2007.

42. Martinez, G. R., Ravanat, J-. L., Cadet, J., Medeiros, M. H. G., Di Mascio, P.
Spiroiminodihydantoin nucleoside formation from 2'-deoxyguanosine oxidation by [18O-labeled] singlet molecular oxygen in aqueous solution. Journal of Mass Spectrometry. , v.42, p.1326 - 1332, 2007.

II- Capítulo em livro.

1. Almeida, E. A., Martinez, G. R., Di Mascio, Paolo
Carotenoid analysis and identification in marine animals In: Oxidative Stress in Aquatic Ecosystems ed.Chichester : John Wiley & Sons, 2012, p. 402-411.

2. Garcia, C. C. M., Angeli, J.P.F., Almeida, E. A., Medeiros, Marisa H. G., Di Mascio, Paolo
Evaluation of DNA adducts formed by lipid peroxidation by-products In: Oxidative Stress in Aquatic Ecosystems ed.Chichester : John Wiley & Sons, 2012, p. 475-486.

3. Almeida, E. A., Grunig, D., Silva, H., Bainy, A. C. D., Freitas, Florencio P., Motta, F. D., Gomes, O.F., Medeiros, M. H. G., Di Mascio, Paolo
Evaluation of glutathione status in aquatic organisms In: Oxidative Stress in Aquatic Ecosystems ed.Chichester : John Wiley & Sons, 2012, p. 381-388.

4. Miyamoto, S., Almeida, E. A., Nogueira, L., Medeiros, M. H. G., Di Mascio, Paolo
Evaluation of malondialdehyde levels In: Oxidative Stress in Aquatic Ecosystems ed.Chichester : John Wiley & Sons, 2012, p. 440-447.

5. Angeli, J.P.F., Martinez, G. R., Motta, F. D., Almeida, E. A., Medeiros, M. H. G., Di Mascio, Paolo
Evaluation of oxidative DNA damage in aquatic animals: comet assays and 8-oxo-7,8-dihidro-2 -deoxyguanosine levels In: Oxidative Stress in Aquatic Ecosystems ed.Chichester : John Wiley & Sons, 2012, p. 465-474.

6. Ronsein, G. E., Martinez, G. R., Almeida, E. A., Miyamoto, S., Medeiros, M. H. G., Di Mascio, Paolo
Role of singlet molecular oxygen in the oxidative damage to biomolecules In: Oxidative Stress in Aquatic Ecosystems ed.Chichester : John Wiley & Sons, 2012, p. 344-358.

7. Almeida, Eduardo Alves, Di Mascio, Paolo
Hypometabolism and antioxidative defense systems in marine invertebrates In: Hypometabolism: Strategies of Survival in Vertebrates and Invertebrates ed.Trivandrum : Research Signpost, 2011, v.0, p. 000-000.

8. Cadet, J., Di Mascio, P.
8-Oxo-7,8-dihydro-2'-deoxyguanosine: A major DNA oxidation product In: Modified nucleosides: in biochemistry , biotechnology and medicine ed.Weinheim : WILEY-VCH Verlag GmbH & Co. KGaA, 2008

9. Harumi, T, Perumal, S R Pandi, Martinez, G R, Di Mascio, P., Hayashi, V
Chromatographic Analyses of Biogenic Melatonin and Its Related Indoleamines In: Melatonin: From Molecules to Therapy ed.New York : Nova Science Publishers, Inc., 2007, p. 3-21.