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Scientific Program

Day One

From 8:00	Registration
8:30	Opening address
8:45-9:30	Chair: Paolo Di Mascio, University of São Paulo, Brazil Plenary Lecture: Helmut Sies, University of Düsseldorf, Germany "Some Reflections on Oxidative Stress and Redox Biology"
9:30-9:55	Session one: Brain/neurodegenerative diseases/inflammation Chair: Junji Terao, The University of Tokushima, Japan "Role of dietary flavonoids on oxidative stress in the central nervous system"
9:55-10:15	De-Xing Hou, Kagoshima University, Japan "Garlic organosulfur compounds as a potential anti-inflammatory agent: molecular and animal evidence"
10:15-10:30	Selected Presentation: Ana Helena S. Oliveira, Federal University of Rio Grande do Norte, Brazil "Proteomic analysis in response to vitamin b6 therapy during oxidative stress induced by penumococcal meningitis in rats"
10:30-11:00	Coffee break
	Session two: Advanced analytical strategies for oxidant and antioxidant analysis Chair: Sayuri Miyamoto, University of São Paulo, Brazil
11:00-11:25	Norberto Peporine Lopes, University of São Paulo, Brazil "Advances in MALDI-MS/MS for polyphenols analysis"
11:25-11:45	Ana Paula Loureiro, University of São Paulo, Brazil "Saliva as a promising matrix for biomonitoring of redox-modified DNA bases"
11:45-12:00	Selected Presentation: Priscila R. Santos, University of São Paulo, Brazil "Behavior of the thermal diffusivity of native and oxidized human low-density lipoprotein solutions"
12:00-14:00	Lunch
14:00-14:25	Session three: Vascular Function and metabolic syndrome Chair: Francisco Laurindo, University of São Paulo, Brazil "Nox Family NADPH oxidases in vascular cells: mechanisms and therapeutic implications".
14:25-14:45	Naomi Osakabe, Shibaura Institute of Technology, Japan "Flavan 3-ols bioactivities on metabolic syndrome-a new angle of observation"
14:45-15:05	Yoshichika Kawai, Nagoya University, Japan "Specific localization of quercetin glucuronides in macrophages: new insights into the biological actions of dietary flavonoids at sites of inflammation"
15:05-15:20	Selected Presentation: Alexandros Papadimitriou, University of Campinas, Brazil "Theobromine cocoa prevents extracellular matrix accumulation via activation of NAD+-dependent deacetylase sirtuin-1 in experimental diabetes mellitus"
15:20-15:35	Selected Presentation: Eliziane Patricio, University of São Paulo, Brazil "Underlying the pro-oxidant effects of urate hydroperoxide on redox modulated proteins: a pivotal role in inflammation"
15:35-16:05	Coffee break
16:05-16:35	Chair: Paolo Di Mascio, University of São Paulo, Brazil Special Lecture: Prof. Jean Cadet, CEA-Grenoble, France "Oxidatively generated damage to cellular DNA"
16:35-18:50	Poster presentation
19:00-21:30	Coquetel/Banquet with Brazilian Music

Day Two

8:45-9:10	Session one: Redox signalling/Cancer/System biology Chair: Hitoshi Ashida, Kobe University, Japan "Effects of flavonoids on the expression system of drug-metabolizing enzymes"
9:10-9:30	Glaucia R. Martinez, Federal University of Paraná, Brazil "Effects of flavonoids and melanin on DNA oxidation by singlet molecular oxygen"
9:30-9:50	Kayoko Shimoi, Shizuoka University, Japan "Chemopreventive effects of flavonoids on the breast cancer development"
9:50-10:10	Diego Bonatto, Federal University of Rio Grande do Sul, Brazil "Toxicological and oxidative stress effects of the different substances in tobacco smoke on human embryonic development by a systems chemo-biology approach"
10:10-10:25	Selected Presentation: Juliana D. Zeidler, Butantan Institute, Brazil "PMA triggers oxidative stress and apoptosis in H-RasV12-dependent human malignant keratinocytes"
10:25-11:00	Coffee break
	Session two: Carotenoids and other phytochemicals Chair: Paolo Di Mascio, University of São Paulo, Brazil
11:00-11:25	Delia Rodrigues Amaya, University of Campinas, Brazil "Processing effects on food carotenoids: Impact on human health"
11:25-11:45	Koichi Aizawa, Kagome Company, Japan "Enhancement of in vivo radical reducing ability of lycopene"
11:45-12:05	Lydia Fumiko Yamaguti, University of São Paulo, Brazil "Occurrence and biosynthesis of biflavonoids"
12:05-12:25	Dulcineia Abdalla, University of São Paulo, Brazil "Identification of microRNAs invloved in the antiangiogenic activity of polyphenols"
12:25-14:00	Lunch
14:00-14:25	Session three: Stress response/Adaptation/Proteasome Chair: Akira Murakami, Kyoto University, Japan "Green tea polyphenol effects on antioxidant enzymes and molecular chaperone"
14:25-14:45	Hirofumi Arai, Kitami Institute of Technology, Japan "Anti-allergic functions of polyphenols"
14:45-15:05	Marilene Demasi, Butantan Institute, Brazil "Redox Control of 20S Proteasome Gating"
15:05-15:20	Selected Presentation: Kaio Vitzel, University of São Paulo, Brazil "The involvement of oxidative stress in skeletal muscle dysfunction of streptozotocin-induced diabetic rats"
15:20-16:00	Coffee break
16:00-16:25	Session four: Biomolecule damage and biomarker analysis Chair: Yoji Kato, Hyogo Prefectural University, Japan "Detection of protein tyrosine modifications by mass spectrometry and antibodies"
16:25-16:45	Sayuri Miyamoto, University of São Paulo, Brazil "Lipid hydroperoxides: singlet oxygen generation and protein modification"
16:45-17:00	Selected Presentation: Thiago C. Genaro-Mattos, University of São Paulo, Brazil "Cytochrome c adduction promoted by cholesterol derived aldehydes – implications to protein-membrane binding"
17:00-17:45	Chair: Marisa H. G. Medeiros, University of São Paulo, Brazil Plenary Lecture: Ohara Augusto, University of São Paulo, Brazil "Oxidative mechanisms in protein aggregation"
17:45	Closing remarks