2019

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1.568 comments 2019-06-12

Transcription activity contributes to the firing of non-constitutive origins in African trypanosomes helping to maintain robustness in S-phase duration.

Scientific Reports

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1.362 comments 2019-27-01

A fluorinated phenylbenzothiazole arrest the Trypanosoma cruzi cell cycle and diminishes the mammalian host-cell infection.

Antimicrobial Agents and Chemotherapy

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1.266 comments 2019-17-10

Experimental evidences that P21 protein controls Trypanosoma cruzi replication and modulates the pathogenesis of infection.

Microbial Pathogenesis

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985 comments 2019-26-04

Pentachloropseudilin Impairs Angiogenesis by Disrupting Actin Cytoskeleton, Integrin Trafficking and Cell Cycle.

ChemBioChem

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1.255 comments 2019-12-07

Dual cellular localization of the Leishmania amazonensis Rbp38 (LaRbp38) explains its affinity for telomeric and mitochondrial DNA.

Biochimie

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1.144 comments 2019-17-06

Increased ROS generation causing apoptotic-like death and autophagy: mechanistic insights into the anti-Leishmania activity of apotent ruthenium (II) complex.

Journal of Inorganic Biochemistry

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1.547 comments 2019-27-04

Action of copper (II) complex with β-diketone and 1,10-phenanthroline (CBP-01) on sarcoma cells and biological effects under cell death.

Biomedicine and pharmacotherapy

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1.599 comments 2019-27-02

Orthologue of the helicase domain of polymerase Theta modulates DNA replication in Trypanosoma cruzi.

Scientific Reports

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1.321 comments 2019-17-01

Overexpression of Trypanosoma cruzi High Mobility Group B protein (TcHMGB) alters the nuclear structure, impairs cytokinesis and reduces the parasite infectivity.

Scientific Reports

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